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It's a new outbreak of Dr. Mario madness! Dr. Mario's back, packing a prescription for fun--and now the frenzied action of the original gets even more frantic with all-new multiplayer modes! Up to four players can go head-to-head, or they can pair up to pile on capsules in Team Battle. Other options let 'em race against time in Score Attack, target flashing viruses in Flash Mode, or test endurance in Marathon play. There's even a new story mode that pits Mario against pilferers trying to profit from his Megavitamins. It's a puzzling epidemic, and Dr. Mario's got the cure!